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Spaeth Lab

This statement reflects my personal values and aligns with ongoing efforts across science and medicine to create a more equitable and accessible research landscape. I believe that science benefits from all perspectives and welcome those from all backgrounds. As a scientist and educator, I am committed to building environments that respect and uplift all people. I will continue to foster belonging, support all voices in STEM, and work toward a future where scientific progress benefits everyone, no matter their background, identity, or circumstance. 

News

2024 in Review: ​

  • Welcome to Snehasish Nag, PhD, a new postdoctoral research fellow in the lab!

  • Congratulation Dr. Sukrati Kanojia on your new position at Eli Lilly!  You're going to do great things!

  • Fantastic new publication in Diabetologia! Congratulations Becca on your last Spaeth lab publication!!! https://link.springer.com/article/10.1007/s00125-024-06211-7

  • Congratulations Dr. Sukrati Kanojia on successfully defending your dissertation! 2nd graduate student to complete their PhD in the Spaeth lab!

  • Welcome to Avinil Das Sharma, the newest Spaeth lab graduate student!

  • Hiring of our newest research technician, Abby Taylor!

 

2023 in Review: ​

  • Newest Spaeth lab publication! Congratulations Sukrati! https://doi.org/10.1080/19382014.2023.2267725 

  • Second R01 submitted to NIDDK! Go Science!

  • Addition of a new research Technician, Kayla Huter!

  • While we are sad to see Meredith leave for Medical School and Kassandra depart for Graduate School, we are happy to announce Kayla Huter, a recent Purdue graduate (Go Boilermakers!), has joined the lab as a Research Technician!

  • The lab's 2nd research paper was published in Diabetes!  https://doi.org/10.2337/db22-0939 

  • Kassandra Sandoval joined the lab as a Research Technician!​
     

2022 in Review: ​

  • Congratulations to Dr. Rebecca Davidson on the successful defense of her dissertation!

  • The lab is now funded by our 1st R01!! (DK129287)

  • Meredith Osmulski joined the lab as a Research Technician!

  • Becca's 1st author manuscript published in the Journal of Molecular Endocrinology! https://doi.org/10.1530/JME-22-0011

  • Fundable score for Dr. Spaeth's R01-A1!

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2021 in Review:

  • Dr. Spaeth submitted his R01A1 to NIDDK

  • Becca's F31 to NIDDK is funded!!

  • Dr. Spaeth received a grant from the Showalter Trust Foundation

 

2020 in Review:

  • Dr. Spaeth received funding for his R03 from the NIDDK

  • Review in Endocrinology authored by Becca and Suki has been published!  https://doi.org/10.1210/endocr/bqaa213

  • Dr. Spaeth received a Biomedical Research Grant award from the IU School of Medicine CTSI

  • Dr. Spaeth received a Pilot and Feasibility grant from IUSM-Center for Diabetes and Metabolic Diseases!

  • Suki has officially joined the lab!!

 

2019 in Review:

  • We are extremely excited to announce that Becca has joined the lab!

  • STEM student Elise Hogarth joined the lab for the summer!

  • Dr. Spaeth's paper on the role of the Swi/Snf chromatin remodeling complex in pancreas formation and adult β cell function was accepted for publication in Diabetes! https://doi.org/10.2337/db19-0349

  • Started the lab in January 2019 and recruited lab technician Nolan Casey!

Spaeth Lab Focus Statement:

Examine how Pdx1-interacting coregulators influence transcription factor function in the developing pancreas, endocrine progenitor cells and mature islet β cells.

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Spaeth Lab Focus Statement:

Early β cell stress associated with diabetes pathogenesis compromises Pdx1:coregulator interactions prior to overt dysfunction. 

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